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Weight Loss

Compounded Semaglutide

A compounded, once-weekly subcutaneous semaglutide injection, prescribed at provider discretion.

Dosage: Provider-directed

Additional dosages available. Your provider will determine the appropriate dose for you.

Compounded Semaglutide

Results

Treatment overview

Once-Weekly Subcutaneous Injection

1

Administered as a subcutaneous injection once per week.

Compounded Formulation

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Prepared by a state-licensed compounding pharmacy under provider prescription.

Active Ingredient

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Active ingredient is semaglutide.

GLP-1 Mechanism

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Semaglutide is a GLP-1 receptor agonist studied for weight management and metabolic health.

Provider-Directed Care

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Whether this medication is appropriate, the dose, and the schedule are determined by your Persona physician.

Built for Long-Term Health

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Care plans are designed to support sustainable health and progress over time, not short-term results.

The treatment

Understanding the treatment

Active Ingredient:

Semaglutide

Compounded semaglutide is a non-FDA-approved formulation prepared by state-licensed compounding pharmacies. It contains semaglutide as an active ingredient and acts as a GLP-1 receptor agonist. Compounded medications are prepared on an individual patient basis under a provider’s prescription and are not interchangeable with FDA-approved products. Whether compounded semaglutide is appropriate for you, the specific dosing schedule, and the duration of treatment are determined by your Persona physician.

Most common: nausea, vomiting, diarrhea, constipation, abdominal pain, decreased appetite, fatigue, and injection-site reactions. Less common but serious: pancreatitis, gallbladder disease, kidney injury, hypoglycemia (with other diabetes meds), worsening diabetic retinopathy, and rare allergic reactions. Seek care for severe or persistent abdominal pain.

Personalized care

The medication is the smaller part

Persona pairs you with a physician, care team, and personalized plan designed to support your body, progress, and long-term goals over time.

Your care team

Board-certified and licensed in your state, with continuity of care throughout your journey.

Ongoing support

Ongoing guidance on usage, lifestyle, side effects, and long-term progress.

Your plan evolves with you

Your treatment plan adjusts over time based on your progress and provider guidance.

Health monitoring

Providers review key health markers over time and adjust care plans when needed.

Questions

Everything you're wondering, answered

Do I need insurance to join Persona Doctors?

No. Persona is designed for transparent cash pay: a monthly price for each medication, shown at checkout before you pay, with no surprise bills. If you do have insurance, we'll happily help with prior authorizations for brand-name medications, and medications are FSA/HSA eligible.

Which medications can my physician prescribe?

Depending on your plan and clinical eligibility: compounded semaglutide and tirzepatide (GLP-1/GLP-1+GIP), oral weight-management medications such as metformin, topiramate, bupropion, and naltrexone, hormone therapies including thyroid, testosterone, and menopause care, and physician-selected peptides. Brand-name options like Wegovy® or Zepbound® can be sent to your local pharmacy when appropriate.

Are compounded medications FDA-approved?

Compounded medications are prepared by state-licensed U.S. pharmacies to a physician's prescription, but they are not FDA-approved and do not undergo FDA review for safety, effectiveness, or quality. Your physician will discuss whether a compounded or brand-name option is right for you.

How does clinical review work?

Your physician reviews your completed intake after checkout. If more information or a phone or video visit is needed, your care team will explain the next step.

How fast will I receive my medication?

After approval and any required verification, eligible orders are sent to the pharmacy. Your portal shows shipment and tracking updates as they become available. Any shipping charges are shown before payment.

Can I cancel, or return an order?

You can cancel, skip, or delay a refill any time before it is charged, and your plan is month-to-month with no lock-ins or cancellation fees — cancelling stops future charges. Once a refill is charged it ships and is not refunded. All dispensed prescription medication is final sale, so we can't accept returns; if a shipment arrives damaged or isn't the medication your provider prescribed, contact us within 7 days of delivery and we'll replace it at no cost. If our physician declines to prescribe treatment, your first purchase is refunded in full.

Your physician is waiting to meet you.

A 10-minute eligibility check is all it takes to begin. No judgment, no waiting rooms. Just care that finally feels personal.

No insurance required · Cancel before your next refill is billed · FSA/HSA eligible